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Profhilo: A Guide to Skin Hydration, Firmness and Rejuvenation

Why Skin Changes With Age

Changes in skin texture and firmness can become more noticeable with age. Skin may look less supple, feel drier or develop a crepey appearance, particularly around the face and neck. Profhilo is an injectable treatment designed to improve skin quality and address skin laxity.

Understanding its ingredients, intended benefits and treatment process can help you decide what to discuss with your dermatologist.

What Is Profhilo?

Profhilo is a hyaluronic acid-based injectable treatment developed by IBSA. It belongs to the category of skin bioremodelling treatments, which aim to improve the condition and firmness of the skin.

The manufacturer indicates Profhilo for tissue remodelling and improvement of skin laxity on the face and neck. Treatment must be administered by a qualified medical professional following an assessment of your skin and medical history.

Key Ingredients in Profhilo

Standard Profhilo contains 64 mg of hyaluronic acid in a 2 ml prefilled syringe, combining:

  • 32 mg of high molecular weight hyaluronic acid
  • 32 mg of low molecular weight hyaluronic acid
These components form stabilised hybrid complexes through IBSA’s patented NAHYCO technology, a thermal process that does not use the chemical cross-linking agent BDDE.

Hyaluronic acid helps retain moisture. In Profhilo, the combination of different molecular weights is designed to support hydration and tissue remodelling.

What Skin Concerns Can Profhilo Address?

Profhilo is intended for people seeking improvement in skin quality, particularly where the skin has begun to lose firmness. Concerns discussed during consultation may include:

  • Mild skin laxity on the face or neck
  • Reduced elasticity and suppleness
  • Dehydrated-looking skin
  • Crepey skin texture
Its main purpose is skin-quality improvement. A clinician should assess whether your concerns are likely to respond to Profhilo or require a different approach. 

Before and after Profhilo: improvement in skin hydration and texture on the cheek, Pandit Clinic, PuneBefore and after Profhilo: smoother-looking skin texture on the cheek, Pandit Clinic, Pune

The Benefits of Profhilo: What You Can Realistically Expect

Improved hydration: Its hyaluronic acid formulation supports moisture retention, which may help skin look and feel more supple.

Support for firmness and elasticity: Profhilo is designed to remodel tissue and improve skin laxity. The manufacturer describes improvements in firmness and tone.

Gradual skin-quality improvement: The treatment aims to produce changes that develop over time. The extent of improvement varies with the individual and the condition of the treated skin.

Profhilo should not be presented as a guaranteed solution for wrinkles, severe sagging or every sign of ageing.

What Happens During a Profhilo Treatment?

The process begins with a consultation. Your clinician reviews your concerns, medical history, allergies, medication and any previous aesthetic procedures before deciding whether treatment is appropriate.

If you proceed, the skin is cleaned and Profhilo is administered through injections at selected points. The injection technique and treatment plan depend on the area being treated.

A commonly recommended initial course consists of two sessions approximately one month apart. Further treatment is based on reassessment rather than a fixed schedule for everyone.

Results and Maintenance After Profhilo

Results should be assessed over time rather than immediately after injection. Early swelling can affect how the treated area looks, so an immediate photograph does not reliably show the final outcome.

The degree and duration of improvement vary. Your clinician can explain realistic expectations, arrange a review and discuss whether maintenance treatment is appropriate.

Before and after Profhilo for the neck: reduced crepey skin and improved firmness, Pandit Clinic, Pune

Side Effects and Recovery: What to Watch For

Possible reactions include redness, swelling, tenderness, bruising and small raised areas around the injection sites. Published safety reporting describes local reactions following treatment; individual recovery can differ.

Follow the specific aftercare instructions provided by your treating clinician, including advice about skincare, makeup, exercise and other procedures. Ask the clinic how to contact them if a reaction is unexpected or worsening.

Is Profhilo Right for You?

Suitability depends on your skin condition, medical history and treatment goals. Tell your clinician about pregnancy or breastfeeding, allergies, ongoing medication and any active infection or inflammation in the proposed treatment area.

A consultation is the best starting point for understanding whether Profhilo can address your concerns and what level of improvement is realistic. At Pandit Clinic, Dr. Sharvari Pandit offers personalised dermatology consultations to help you determine whether Profhilo is appropriate for your skin.

This article provides general information about standard Profhilo and does not replace an individual medical assessment.

Frequently Asked Questions About Profhilo Treatment

What is Profhilo used for?

Profhilo is an injectable treatment designed to improve skin hydration, firmness and elasticity, particularly where the face or neck shows skin laxity.

What is the main ingredient?

Standard Profhilo contains 64 mg of hyaluronic acid per 2 ml syringe, combining high and low molecular weight hyaluronic acid.

Is Profhilo a cream or serum?

No. It is a professional injectable treatment administered by a qualified medical practitioner.

How many sessions are usually needed?

A typical initial course involves two sessions approximately one month apart. Your clinician will personalise the treatment plan.

When will I see results?

Changes develop gradually. Your clinician will explain when to assess results based on your skin condition and treatment schedule.

Are the results permanent?

Results are temporary and vary between individuals. Maintenance treatment may be considered after a clinical review.

Does the treatment hurt?

You may experience discomfort or tenderness during and after the injections. Discuss comfort measures with your clinician beforehand.

What side effects can occur?

Possible reactions include redness, swelling, tenderness, bruising and small raised areas at the injection sites. Contact your clinic if symptoms worsen or concern you.

Can Profhilo completely remove wrinkles or sagging?

Complete correction should not be expected. Profhilo aims to improve skin quality and laxity; more pronounced concerns may require a different treatment.

What should I discuss before treatment?

Tell your clinician about your medications, allergies, previous aesthetic procedures, pregnancy or breastfeeding, and any infection or inflammation in the treatment area.

What aftercare is required?

Follow your clinician's instructions about skincare, makeup, exercise and other procedures. Recovery advice should be tailored to your treatment.

How do I know whether Profhilo is suitable for me?

A qualified dermatologist or aesthetic medical practitioner should assess your skin, medical history and expectations before recommending treatment.

Dr Sharvari Pandit Dermatologist, Cosmetologist, Trichologist

Dr. Sharvari Pandit

MBBS, DDV (Skin & VD), MD (SEY )

Meet the Doctor

Dermatologist, Venereologist & Trichologist

Dr. Sharvari Pandit is a Consultant Dermatologist, Venereologist & Trichologist at Pandit Clinic. She has an experience of more than 10 years and acts as a visiting consultant at MMF’s Joshi Hospital, Ramkrishna Math Polyclinic, Skin Solutions clinic, Sanjeevan Hospital, Police Hospital, Pune and SRPF’s Hospital, Pune. Dr. Sharvari’s areas of special interest include aesthetic surgeries, Laser hair reduction, skin and facial rejuvenation, anti-ageing treatments (like HA Fillers and Botulinum Toxin) and hair fall treatments.

Dr Sharvari Pandit Dermatologist, Cosmetologist, Trichologist

Dr. Sharvari Pandit

MBBS, DDV (Skin & VD), MD (SEY )

Meet the Doctor

Dermatologist, Venereologist & Trichologist

Dr. Sharvari Pandit is a Consultant Dermatologist, Venereologist & Trichologist at Pandit Clinic. She has an experience of more than 10 years and acts as a visiting consultant at MMF’s Joshi Hospital, Ramkrishna Math Polyclinic, Skin Solutions clinic, Sanjeevan Hospital, Police Hospital, Pune and SRPF’s Hospital, Pune. Dr. Sharvari’s areas of special interest include aesthetic surgeries, Laser hair reduction, skin and facial rejuvenation, anti-ageing treatments (like HA Fillers and Botulinum Toxin) and hair fall treatments.

Dr. Sharvari Pandit

Dr Sharvari Pandit, Consultant Dermatologist and trichologist, has the latest experience with aesthetic lasers & Cosmetology. Her areas of interest include hair regrowth, Aesthetic surgeries, Skin rejuvenation, Anti-ageing and Pigmentations. She has specialized in treatment for Skin diseases, Vitiligo treatments, Acne scar treatments and hair reduction using the latest lasers.